CBD has shown potential to help with cardiovascular disease, either directly or indirectly. Researchers have examined this from various perspectives, and their findings could be valuable for those interested in improving heart and vascular health. This review will explore the most relevant and recent studies on CBD and cardiovascular health.

Overview of CBD Treatment for Cardiovascular Disease

The benefits of CBD for cardiovascular health warrant further investigation. While scientists aren’t entirely sure what drives CBD’s apparent heart benefits, reducing inflammation might play a role. Additionally, CBD has shown potential to protect the heart from harmful substances and may even improve the mitochondrial function of heart cells. Although only one human trial has been conducted, laboratory research remains a crucial part of understanding CBD’s effects.

Recent Research on CBD and Cardiovascular Disease

2023: CBD Supplementation Lowers Blood Pressure by Modulating the Sympathochromaffin System
The only human clinical study on this topic so far is worth noting. This five-week trial involved 54 patients and focused on how CBD affects cate statin, a peptide that increases as heart disease progresses. The study found that CBD administration over five weeks led to a reduction in serum catestatin levels.

2022: Cannabidiol Reduces Myocardial Ceramide Synthesis in a High-Fat Diet-Induced Obesity Rat Model
Ceramide pathways in the heart are commonly associated with cardiovascular disease, especially in obese individuals. In this animal study, researchers found that CBD prevented the formation of new ceramide pathways, suggesting that CBD might prevent heart disease through an unknown mechanism.

2022: Cannabidiol’s Anti-Inflammatory Effects on Lipopolysaccharides and Cardiac Sodium Channels
In this study, CBD was tested in a sepsis model to determine if it could reduce the entry of toxic substances into the heart and prevent cardiotoxicity. Using human cells instead of live subjects, researchers discovered that CBD might protect against sepsis-induced inflammation and arrhythmias by inhibiting cytokines, which are pro-inflammatory chemicals that can worsen cardiovascular disease.

2021: Cannabidiol Reduces Pulmonary Arterial Hypertension by Improving Mitochondrial Function in Vascular Smooth Muscle Cells
Rodent models showed that CBD could reduce hypertension by enhancing mitochondrial function and lowering oxidative stress. The findings were generally positive, and researchers believe that CBD could play a significant role in treating hypertension.

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